Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534794 | 0.76 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL4891492 | 0.76 | ALDH1A1 (0.49) | ALDH1A1GLAVDRTDP1TP53 | |
| SCHEMBL7239384 | 0.76 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL11520782 | 0.75 | ALDH1A1 (0.41) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL11508884 | 0.74 | IDO1 (0.47) | ALDH1A1GLAVDRTDP1TP53 | |
| SCHEMBL9386148 | 0.74 | ALDH1A1 (0.47) | ALDH1A1GLAVDRTDP1TP53 | |
| SCHEMBL7679677 | 0.71 | ALDH1A1 (0.38) | ALDH1A1GLAVDRTDP1TP53 | |
| SCHEMBL7679673 | 0.71 | ALDH1A1 (0.38) | ALDH1A1GLAVDRTDP1TP53 | |
| SCHEMBL5070273 | 0.71 | ALDH1A1 (0.61) | ALDH1A1GLAVDRTDP1TP53 | |
| SCHEMBL1715947 | 0.70 | ALDH1A1 (0.65) | ALDH1A1GLATDP1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171446-A | Indazole compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1979-10-16 | — | — | US | disclosed |