Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524887 | 0.83 | CA12 (0.56) | ABCC1SMN1; SMN2ALPLGAAHPGD | |
| SCHEMBL11528815 | 0.83 | ABCC1 (0.58) | ABCC1TAAR1AOC3SIGMAR1NPY5R | |
| SCHEMBL7226798 | 0.75 | AOC3 (0.57) | ABCC1TAAR1AOC3SIGMAR1NPY5R | |
| SCHEMBL28128867 | 0.74 | ABCC1 (0.50) | ABCC1TAAR1SMN1; SMN2AOC3SIGMAR1 | |
| SCHEMBL11527812 | 0.74 | GAA (0.65) | SMN1; SMN2ALPLGAAHPGDALOX12 | |
| SCHEMBL10090413 | 0.73 | KMT2A (0.57) | SMN1; SMN2ALPLGAAHPGDALOX12 | |
| SCHEMBL2796515 | 0.72 | TAAR1 (0.52) | ABCC1TAAR1AOC3SIGMAR1NPY5R | |
| SCHEMBL14464159 | 0.72 | KMT2A (0.55) | SMN1; SMN2ALPLGAAHPGDALOX12 | |
| SCHEMBL28343162 | 0.72 | SMN1; SMN2 (0.51) | TAAR1SMN1; SMN2ALPLGAAHPGD | |
| SCHEMBL11530304 | 0.71 | ALDH1A1 (0.60) | SMN1; SMN2GAAHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |