Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MGLL | Q99685 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527812 | 0.93 | GAA (0.65) | ALDH1A1MGLLGAAMEN1KMT2A | |
| SCHEMBL11662593 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MGLLGAAMAPK1MAPT | |
| SCHEMBL5455476 | 0.81 | MAPK1 (0.81) | ALDH1A1MGLLGAAMAPK1MAPT | |
| SCHEMBL11524887 | 0.81 | CA12 (0.56) | ALDH1A1MGLLGAAMEN1KMT2A | |
| SCHEMBL965736 | 0.79 | LMNA (0.64) | ALDH1A1MGLLMAPK1MEN1KMT2A | |
| SCHEMBL19494112 | 0.79 | L3MBTL1 (0.68) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL3190624 | 0.77 | ALDH1A1 (0.69) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL21603953 | 0.77 | MGLL (0.66) | ALDH1A1MGLLMAPK1MAPTMEN1 | |
| SCHEMBL22559961 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPK1MEN1KMT2ALMNA | |
| SCHEMBL28659300 | 0.75 | MGLL (0.64) | ALDH1A1MGLLMAPK1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |