SCHEMBL11528402

SCHEMBL11528402

CCN(CCS(=O)(=O)O)c1cccc(N)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
PIK3CA P42336 1/20 0.36
TTR P02766 1/20 0.34
NR3C1 P04150 5/20 0.34
PGR P06401 1/20 0.32
NR3C2 P08235 1/20 0.32
AR P10275 1/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
S100B P04271 1/20 0.31
ESR1 P03372 1/20 0.31
KCNH2 Q12809 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL8624039 0.86 MEN1 (0.38) CYP3A4TSHRPIK3CATTRNR3C1
SCHEMBL6472907 0.79 CYP3A4 (0.52) CYP3A4TSHRPIK3CANR3C1ALDH1A1
SCHEMBL9631140 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDMEN1
Hydrochloric Acid SCHEMBL3385173 0.78 CYP3A4 (0.50) CYP3A4TSHRPIK3CANR3C1ALDH1A1
Hydrochloric Acid SCHEMBL6472903 0.78 CYP3A4 (0.50) CYP3A4TSHRPIK3CANR3C1ALDH1A1
Sulfuric Acid SCHEMBL30532227 0.72 HSD17B10 (0.39) CYP3A4TSHRTTRALDH1A1HPGD
Sulfuric Acid SCHEMBL1304808 0.72 HSD17B10 (0.39) CYP3A4TSHRTTRALDH1A1HPGD
SCHEMBL29938933 0.71 S100B (0.64) CYP3A4TSHRARALDH1A1HPGD
SCHEMBL9768909 0.71 LMNA (0.44) ALDH1A1KMT2AL3MBTL1ESR1HSD17B10
SCHEMBL2156882 0.71 S100B (0.64) CYP3A4TSHRARALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4145299-A GOOD DISPERSION STABILITY; LOW CONTRAST, HIGH RESOLUTION IMAGES AND LIGHT STABILITY EASTMAN KODAK COMPANY (US) 1979-03-20 US disclosed