Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323178 | 0.86 | CA1 (0.48) | CA1CA2CA12CA9CASP6 | |
| SCHEMBL7084160 | 0.83 | ALDH1A1 (0.54) | CA1CA2CA12CA9CASP6 | |
| SCHEMBL9320034 | 0.82 | CA1 (0.51) | CA1CA2CA12CA9CASP6 | |
| SCHEMBL11525372 | 0.80 | CA1 (0.45) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL9809412 | 0.79 | ALDH1A1 (0.47) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL24203633 | 0.78 | PRMT1 (0.62) | CA1CA2CA12CA9CASP6 | |
| SCHEMBL8899784 | 0.76 | GAA (0.46) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL11419583 | 0.75 | ALDH1A1 (0.59) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL2126663 | 0.73 | MEN1 (0.71) | MEN1KMT2AMAPK1LMNAPOLB | |
| SCHEMBL11670052 | 0.73 | ALDH1A1 (0.41) | CASP6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139527-A | FOR LEATHER, CELLULOSE, WOOL, SILK, POLYAMIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |