Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | CTSG | P08311 | 3/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030508 | 0.98 | MMP2 (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL3677232 | 0.98 | MMP2 (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL9809413 | 0.98 | MMP2 (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL5271379 | 0.98 | MMP2 (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL5275919 | 0.98 | MMP2 (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL5340196 | 0.98 | MMP2 (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL11245897 | 0.98 | MMP2 (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL1899408 | 0.95 | POLB (0.49) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL7066806 | 0.91 | MDM2 (0.52) | CES2CES1MDM2PRSS1CTSG | |
| SCHEMBL9352547 | 0.90 | CES2 (0.50) | CES2CES1MDM2PRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139717-A | 1,3-Dicarbonyl compounds | TEIJIN LIMITED (JP) | 1979-02-13 | — | — | US | disclosed |
| US-4009196-A | HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS | TEIJIN LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |