SCHEMBL11528753

SCHEMBL11528753

Cc1ccccc1-c1nc2cc(Cl)ccc2[nH]1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.67
RAB9A P51151 5/20 0.67
ALDH1A1 P00352 4/20 0.67
HPGD P15428 3/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
HTT P42858 1/20 0.67
NPSR1 Q6W5P4 1/20 0.67
NPBWR1 P48145 2/20 0.51
KDM4E B2RXH2 3/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50
AMY1A P0DUB6 5/20 0.48
ATM Q13315 1/20 0.48
ERAP1 Q9NZ08 1/20 0.48
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22955884 0.88 AMY1A (0.55) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL13405888 0.84 ALDH1A1 (0.71) NPC1RAB9AALDH1A1HPGDNPBWR1
SCHEMBL13406025 0.84 ALDH1A1 (0.58) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL3200875 0.82 SMN1; SMN2 (0.67) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL3336164 0.82 ALDH1A1 (0.67) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL7393988 0.82 F7 (0.55) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL10041675 0.82 NPC1 (0.62) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL22956044 0.82 KDM4E (0.59) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL31289457 0.82 SMN1; SMN2 (0.67) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL23758274 0.81 AMY1A (0.64) AMY1AMAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4152163-A Silver halide photographic emulsion containing cyanine and hemicyanine sensitizing dyes FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US disclosed