Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788080 | 0.67 | CYP2C9 (0.40) | LMNAHPGDPTBP1ALDH1A1CYP1A2 | |
| SCHEMBL10788109 | 0.65 | ALDH1A1 (0.38) | LMNAHPGDPTBP1ALDH1A1HTT | |
| SCHEMBL22504186 | 0.62 | SLC1A2 (0.30) | — | |
| SCHEMBL22558757 | 0.61 | LMNA (0.41) | LMNAMAPK1ALDH1A1SRCCYP2D6 | |
| Camphoric Acid SCHEMBL31154319 | 0.61 | NPSR1 (0.50) | LMNAMAPK1ALDH1A1HTTNPSR1 | |
| SCHEMBL31618321 | 0.61 | ALDH1A1 (0.38) | LMNAMAPK1HPGDALDH1A1SRC | |
| SCHEMBL19809411 | 0.60 | LMNA (0.39) | LMNAMAPK1ALDH1A1KMT2ASRC | |
| SCHEMBL15106438 | 0.59 | SRC (0.46) | LMNAMAPK1HPGDALDH1A1KMT2A | |
| SCHEMBL1312762 | 0.58 | SRC (0.64) | LMNAMAPK1HPGDALDH1A1KMT2A | |
| SCHEMBL23375795 | 0.57 | LMNA (0.49) | LMNAALDH1A1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145437-A | LACTONES, ANTIULCER AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |