Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20988105 | 0.78 | MAPT (0.35) | ALDH1A1MAPTALDH2 | |
| SCHEMBL28103264 | 0.77 | MAPT (0.31) | ALDH1A1MAPTALDH2 | |
| SCHEMBL12226585 | 0.74 | TP53 (0.41) | TSHRTP53 | |
| SCHEMBL11193257 | 0.73 | LMNA (0.38) | TSHRLMNAALDH1A1CYP2D6MAPT | |
| SCHEMBL28181120 | 0.72 | AOC3 (0.31) | — | |
| SCHEMBL6546657 | 0.72 | TSHR (0.46) | TSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL9949162 | 0.71 | MAPT (0.39) | TSHRLMNAMAPT | |
| SCHEMBL5072392 | 0.71 | ALDH1A1 (0.41) | TSHRLMNAALDH1A1CYP2D6MAPT | |
| SCHEMBL8506946 | 0.70 | — | — | |
| SCHEMBL11642303 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160819-A | APPLYING PROTECTIVE AGENT COMPRISING CONDENSATION PRODUCT OF ALKYLENE OXIDE AND POLYAMINE | CINCINNATI MILACRON, INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4141966-A | APPLYING TO SKIN A PROTECTIVE AGENT CONTAINING TWO POLAR GROUPS; PROTECTION FROM ALLERGIC CONTACT DERMATITIS | CINCINNATI MILACRON (US) | 1979-02-27 | — | — | US | disclosed |
| US-4137301-A | Method of inhibiting skin irritation | CINCINNATI MILACRON, INC. (US) | 1979-01-30 | — | — | US | disclosed |
| US-4076799-A | POISON IVY, AMINE SALT OF DIMERIZED ACID | CINCINNATI MILACRON, INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4075318-A | POLYESTERS, DIMER ACIDS AND DERIVATIVES | CINCINNATI MILACRON, INC. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4067345-A | Method and compositions for retarding chemical damage to hair with treating agents containing two or more polar groups | CINCINNATI MILACRON INC. (US) | 1978-01-10 | — | — | US | disclosed |
| US-4045550-A | ESTER AND POLYESTER PROTECTIVE AGENTS | CINCINNATI MILACRON INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-3981990-A | Skin protective compositions | CINCINNATI MILACRON, INC. (US) | 1976-09-21 | — | — | US | disclosed |