Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | STAT5B | P51692 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715518 | 0.89 | PTGIR (0.37) | STAT5BSTAT3MLYCDHDAC1HDAC8 | |
| SCHEMBL11531092 | 0.84 | CA2 (0.40) | STAT5B | |
| SCHEMBL11531682 | 0.84 | STAT5B (0.37) | STAT5BESR1STAT3MLYCD | |
| SCHEMBL3349318 | 0.82 | MLYCD (0.41) | MLYCD | |
| SCHEMBL895556 | 0.80 | MLYCD (0.39) | MIFESR1ESR2MLYCD | |
| SCHEMBL12275098 | 0.80 | ESR1 (0.41) | ESR1ESR2MLYCDACHEKDM4E | |
| SCHEMBL4832488 | 0.80 | HDAC1 (0.48) | ACHEHDAC1HDAC8HDAC6 | |
| SCHEMBL27650496 | 0.79 | BRD4 (0.42) | MIFESR1ESR2ACHEKDM4E | |
| SCHEMBL6302058 | 0.79 | HDAC1 (0.36) | MLYCDHDAC1HDAC8HDAC6 | |
| SCHEMBL11052501 | 0.79 | NQO2 (0.39) | STAT5BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133882-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |