SCHEMBL11528866

SCHEMBL11528866

C=C1C=CCC2C(=O)N(C3CCC(C)CC3)C(=O)C12

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
HPGD P15428 1/20 0.37
HTR7 P34969 1/20 0.36
POLB P06746 2/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527945 0.85 ALDH1A1 (0.42) ALDH1A1HPGDHTR7POLBLMNA
SCHEMBL11528994 0.73 ACHE (0.33)
SCHEMBL13286154 0.70 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11798556 0.70 HSD17B10 (0.36) ALDH1A1HPGDLMNAKMT2A
SCHEMBL11584760 0.70 ALDH1A1 (0.38) ALDH1A1LMNAKMT2A
SCHEMBL11583580 0.68 ATM (0.35) ALDH1A1HPGDPOLBLMNAKMT2A
SCHEMBL22000066 0.66 ALDH1A1 (0.56) ALDH1A1POLBLMNASMN1; SMN2PKM
SCHEMBL12248262 0.66 ALDH1A1 (0.38) ALDH1A1HPGDPOLBLMNASMN1; SMN2
SCHEMBL11594146 0.66 GAA (0.33) KMT2A
SCHEMBL11529894 0.66 SMN1; SMN2 (0.40) ALDH1A1HPGDHTR7POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132750-A RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES SHOWA DENKO K.K. (JP) 1979-01-02 US disclosed
US-4105608-A HIGH IMPACT COMPOSITION OF RING-OPENING POLYMERIZATION PRODUCT SHOWA DENKO K.K. (JP) 1978-08-08 US disclosed
US-4059561-A AND A HALOGEN COMPOUND SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed
US-4028482-A LOW VISCOSITY POLYALKENAMER SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-06-07 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3959234-A CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-05-25 US disclosed