Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705158 | 0.91 | TSHR (0.52) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL7702223 | 0.88 | SLC6A2 (0.54) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL27375200 | 0.86 | CYP2D6 (0.52) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL28226428 | 0.82 | FFAR4 (0.53) | CYP2D6BLMMEN1TSHRCYP2C19 | |
| SCHEMBL7705213 | 0.81 | GSTK1 (0.50) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL2935706 | 0.81 | ABCC4 (0.54) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL21628120 | 0.81 | ABCC4 (0.54) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL6422160 | 0.81 | ABCC4 (0.54) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL26554829 | 0.81 | SLC6A2 (0.47) | CYP2D6NFKB1SLC6A2SLC6A4BLM | |
| SCHEMBL13291956 | 0.79 | CYP2D6 (0.60) | CYP2D6NFKB1SLC6A2SLC6A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167520-A | Process for preparing organotin trihalides | AKZO N.V. (NL) | 1979-09-11 | — | — | US | disclosed |