Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476963 | 0.74 | TSHR (0.36) | TSHRALDH1A1TP53HSD17B10HPGD | |
| SCHEMBL16679247 | 0.74 | TSHR (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9811791 | 0.74 | THRB (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL127482 | 0.72 | POLB (0.43) | ALDH1A1 | |
| SCHEMBL4381366 | 0.71 | ALDH1A1 (0.58) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9811787 | 0.71 | TSHR (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12192386 | 0.71 | TSHR (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL18145197 | 0.70 | PPM1B (0.38) | TSHRALDH1A1HSD17B10HPGDPPM1B | |
| SCHEMBL5296610 | 0.70 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7199881 | 0.69 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140606-A | Process for preparing a polymerizable (meth) acrylate oligomer | SHOWA DENKO K.K. (JP) | 1979-02-20 | — | — | US | claimed |