Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18286925 | 0.88 | TDP1 (0.58) | TDP1NPSR1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL22712664 | 0.82 | TDP1 (0.40) | TDP1NPSR1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL30486812 | 0.82 | NPSR1 (0.59) | TDP1NPSR1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL419987 | 0.82 | NPSR1 (0.59) | TDP1NPSR1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL6886942 | 0.81 | TSHR (0.60) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL10979000 | 0.81 | TSHR (0.58) | TDP1NPSR1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL15034656 | 0.81 | TDP1 (0.67) | TDP1NPSR1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL27828029 | 0.81 | L3MBTL1 (0.56) | TDP1NPSR1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6886786 | 0.79 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL2960078 | 0.79 | TDP1 (0.48) | TDP1NPSR1TSHRSMN1; SMN2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171425-A | ANIONIC CATALYST, 2-PYRROLIDONE OR E-CAPROLACTAM | CHEVRON RESEARCH COMPANY (US) | 1979-10-16 | — | — | US | disclosed |