Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30486812 | 1.00 | NPSR1 (0.59) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| Nitrous Acid SCHEMBL29013334 | 0.91 | NPSR1 (0.55) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL9336413 | 0.87 | NPSR1 (0.59) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL23929022 | 0.85 | NPSR1 (0.57) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL28552981 | 0.85 | NPSR1 (0.57) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL2581018 | 0.83 | NPSR1 (0.56) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL2956140 | 0.83 | NPSR1 (0.60) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL4008025 | 0.83 | NPSR1 (0.56) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL8331183 | 0.83 | NPSR1 (0.60) | NPSR1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL8733188 | 0.83 | NPSR1 (0.56) | NPSR1HSD17B10TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-11787903-B2 | Highly strong and tough photo-crosslinked hydrogel material and its preparation and application | ZHONGSHAN GUANGHE MEDICAL TECHNOLOGY CO., LTD (CN) | 2023-10-17 | — | — | US | disclosed |
| US-20230288804-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-14 | — | — | US | disclosed |
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-20230130864-A1 | HIGHLY STRONG AND TOUGH PHOTO-CROSSLINKED HYDROGEL MATERIAL AND ITS PREPARATION AND APPLICATION | Zhongshan Guanghe Medical Technology Co., Ltd. (CN) | 2023-04-27 | — | — | US | disclosed |
| CN-115838348-A | Synthetic method and application of benzopyrrole quaternary ammonium hydroxide | 万华化学集团股份有限公司 | 2023-03-24 | — | — | CN | disclosed |
| US-20220009875-A1 | NITRATION | ETH ZURICH (CH) | 2022-01-13 | — | — | US | disclosed |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-20210347742-A1 | CFTR REGULATORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-11 | — | — | US | disclosed |
| US-5104944-A | Redox system | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |
| US-5045159-A | Derivatives of compounds containing a carbonyl group conjugated to an aromatic moiety and electrophilic methods of fabrication thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| US-5021129-A | Multilayer structures of different electroactive materials and methods of fabrication thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0419804-A2 | Multilayer structures of different electroactive materials and methods of fabrication thereof | International Business Machines Corporation (US) | 1991-04-03 | — | — | EP | disclosed |
| EP-0409002-A2 | Process for nucleophilic derivatization of materials having an imide group conjugated to an aromatic moiety | International Business Machines Corporation (US) | 1991-01-23 | — | — | EP | disclosed |
| EP-0409003-A2 | Derivatives of compounds containing a carbonyl group conjugated to an aromatic moiety and electrophilic methods of fabrication thereof | International Business Machines Corporation (US) | 1991-01-23 | — | — | EP | disclosed |
| EP-0374487-A2 | Method for conditioning an organic polymeric material | International Business Machines Corporation (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4496782-A | STOICHIOMETRY; DINITROTOLUENES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-01-29 | — | — | US | disclosed |
| US-4132611-A | Addition of organic electrophiles to carbon acids via catalysis by electrogenerated bases | MONSANTO COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4072583-A | Electrolytic carboxylation of carbon acids via electrogenerated bases | MONSANTO COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009875-A1 | NITRATION | NOS1, NOS2, NOS3 | NPSR1 261/4885HSD17B10 2552/4885TDP1 1637/4885 |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | NPSR1 3655/4885HSD17B10 423/4885TDP1 945/4885 |
| US-20210347742-A1 | CFTR REGULATORS AND METHODS OF USE THEREOF | CFTR, SLC26A4, CLCN2 | NPSR1 858/4885HSD17B10 2372/4885TDP1 2925/4885 |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | NPSR1 3657/4885HSD17B10 3100/4885TDP1 1450/4885 |
| US-11655203-B2 | Nitration | NOS1, NOS2, NOS3 | NPSR1 261/4885HSD17B10 2552/4885TDP1 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.