SCHEMBL11529436

SCHEMBL11529436

C[C@@H]1C[C@@H](OC(C)(C)O[C@@H]2C[C@@H](C)C(=O)C(C)(C)C2)CC(C)(C)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11535631 1.00
SCHEMBL9462697 0.92
SCHEMBL9693621 0.92
SCHEMBL8946853 0.77 PPM1D (0.36)
SCHEMBL955952 0.77 PPM1D (0.36)
SCHEMBL9462890 0.74 TSHR (0.35)
SCHEMBL2689523 0.69
SCHEMBL8165368 0.67 ENO1 (0.32)
SCHEMBL5713354 0.67 ENO1 (0.32)
SCHEMBL6720724 0.67 ENO1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4156100-A INTERMEDIATES FOR OPTICALLY ACTIVE CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1979-05-22 US disclosed
US-4153615-A Method of producing coloring agents HOFFMANN-LA ROCHE INC. (US) 1979-05-08 US disclosed
US-4095038-A INTERMEDIATES IN THE PRODUCTION OF CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1978-06-13 US disclosed
US-4072715-A CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1978-02-07 US disclosed
US-4026949-A INTERMEDIATES FOR CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1977-05-31 US disclosed
US-3988205-A BY FERMENTATIVELY HYDROGENATING AND REDUCING KETOISOPHORONE HOFFMANN-LA ROCHE INC. (US) 1976-10-26 US disclosed