SCHEMBL11529645

SCHEMBL11529645

Cc1ncc(CCl)c(CCl)c1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
KDM4E B2RXH2 2/20 0.58
HPGD P15428 2/20 0.58
HSD17B10 Q99714 1/20 0.58
LMNA P02545 2/20 0.53
KMT2A Q03164 3/20 0.43
PDXK O00764 2/20 0.43
MEN1 O00255 1/20 0.43
AOX1 Q06278 1/20 0.43
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
GAA P10253 1/20 0.37
ESR1 P03372 1/20 0.36
PTGS1 P23219 1/20 0.36
ACP1 P24666 1/20 0.36
PDE4A P27815 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31643772 1.00 ALDH1A1 (0.58) ALDH1A1KDM4EHPGDHSD17B10LMNA
Hydrochloric Acid SCHEMBL11529236 0.98 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDHSD17B10LMNA
Hydrochloric Acid SCHEMBL31300104 0.98 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL11016270 0.89 KDM4E (0.76) ALDH1A1KDM4EHPGDHSD17B10LMNA
Hydrochloric Acid SCHEMBL11449750 0.87 ALDH1A1 (0.73) ALDH1A1KDM4EHPGDHSD17B10LMNA
Hydrochloric Acid SCHEMBL11449639 0.85 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL14750261 0.84 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL21657969 0.82 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10LMNA
Hydrochloric Acid SCHEMBL11450712 0.80 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL20502352 0.74 KDM4E (0.92) ALDH1A1KDM4EHPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228811-A1 Triester Compounds And Methods Of Use Thereof LIFEMINE THERAPEUTICS, INC. 2025-07-17 US disclosed
EP-4008718-A1 HETEROARYLAMIDOPYRIDINOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE Innovo Therapeutics Inc. (KR) 2022-06-08 EP disclosed
WO-2021060890-A1 HETEROARYLAMIDOPYRIDINOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE 주식회사 이노보테라퓨틱스 2021-04-01 WO disclosed
WO-2019194556-A1 NOVEL 6-HETEROARYLAMINO-2,4,5-TRIMETHYLPYRIDIN-3-OL COMPOUND, OR PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES AND AUTOIMMUNE DISEASES COMPRISING SAME 영남대학교 산학협력단 2019-10-10 WO disclosed
WO-2018131924-A1 PYRIDINOL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT 영남대학교 산학협력단 2018-07-19 WO disclosed
US-9994519-B2 Synthetic antioxidants and their uses LU YANSONG (US) 2018-06-12 US disclosed
US-9994519-B2 Synthetic antioxidants and their uses LU YANSONG (US) 2018-06-12 US disclosed
US-9802897-B2 Amidopyridinol derivative or pharmaceutically acceptable salt thereof and pharmaceutical composition comprising same as active component RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (KR) 2017-10-31 US disclosed
WO-2017123038-A1 PYRIDINOL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT 영남대학교 산학협력단 2017-07-20 WO disclosed
US-20150336884-A1 NOVEL SYNTHETIC ANTIOXIDANTS AND THEIR USES LU YANSONG (US) 2015-11-26 US disclosed
WO-2013095060-A1 6-AMINOPYRIDINE-3-OL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENTS FOR PREVENTING OR TREATING DISEASES CAUSED BY ANGIOGENESIS 영남대학교 산학협력단 (KR) 2013-06-27 WO disclosed
US-4144239-A Manufacture of pyridoxin BASF AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336884-A1 NOVEL SYNTHETIC ANTIOXIDANTS AND THEIR USES TXNRD2, HMGCR, GSR ALDH1A1 1163/4885KDM4E 4476/4885HPGD 86/4885
US-20250228811-A1 Triester Compounds And Methods Of Use Thereof CYP46A1, CYP17A1, CYP27A1 ALDH1A1 1167/4885KDM4E 2546/4885HPGD 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.