Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526814 | 1.00 | LMNA (0.38) | LMNACYP3A4HTR1AADRA2AMEN1 | |
| SCHEMBL11528379 | 1.00 | LMNA (0.38) | LMNACYP3A4HTR1AADRA2AMEN1 | |
| SCHEMBL11527969 | 1.00 | LMNA (0.38) | LMNACYP3A4HTR1AADRA2AMEN1 | |
| SCHEMBL28292462 | 0.91 | LPAR3 (0.40) | LMNACYP3A4HTR1AADRA2AMEN1 | |
| SCHEMBL11527505 | 0.89 | LMNA (0.34) | LMNACYP3A4HTR1AADRA2AMEN1 | |
| SCHEMBL11533263 | 0.86 | ESR1 (0.45) | ESR1LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL11803366 | 0.85 | HMGCR (0.46) | LMNACYP3A4HTR1AADRA2AMEN1 | |
| SCHEMBL11646066 | 0.84 | LPAR3 (0.38) | ESR1LPAR3LPAR2LPAR1HMGCR | |
| SCHEMBL11646828 | 0.84 | LPAR3 (0.38) | ESR1LPAR3LPAR2LPAR1HMGCR | |
| SCHEMBL11526335 | 0.84 | CYP2C19 (0.40) | LMNACYP3A4HTR1AADRA2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161473-A | 2,4,6-Trialkyl-3-hydroxyphenylalkane phosphonate and phosphinate stabilizers | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-3962376-A | STABILIZERS, OXIDATION RESISTANCE, HEAT RESISTANCE, RADIATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |