SCHEMBL11533263

SCHEMBL11533263

CCCCCCCCCCCCCCCCCCOP(=O)(Cc1c(C)cc(C)c(O)c1C)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.45
LPAR3 Q9UBY5 6/20 0.41
LPAR2 Q9HBW0 6/20 0.41
LPAR1 Q92633 2/20 0.41
PGK1 P00558 1/20 0.41
PGK2 P07205 1/20 0.41
S1PR2 O95136 1/20 0.37
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
GSTA1 P08263 2/20 0.35
GSTP1 P09211 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528379 0.86 LMNA (0.38) ESR1LPAR3LPAR2LPAR1PGK1
SCHEMBL11529863 0.86 LMNA (0.38) ESR1LPAR3LPAR2LPAR1PGK1
SCHEMBL11526814 0.86 LMNA (0.38) ESR1LPAR3LPAR2LPAR1PGK1
SCHEMBL11527969 0.86 LMNA (0.38) ESR1LPAR3LPAR2LPAR1PGK1
SCHEMBL11594658 0.76 THRA (0.44) ESR1LPAR3LPAR2LPAR1S1PR2
SCHEMBL28292462 0.76 LPAR3 (0.40) ESR1LPAR3LPAR2LPAR1PGK1
SCHEMBL11527505 0.76 LMNA (0.34) ESR1LPAR3LPAR2LPAR1
SCHEMBL10988240 0.76 ESR1 (0.49) ESR1LPAR2S1PR2S1PR1S1PR3
SCHEMBL19618688 0.75 ESR1 (0.42) ESR1LPAR3LPAR2LPAR1S1PR2
SCHEMBL11690877 0.75 ESR1 (0.42) ESR1LPAR3LPAR2LPAR1S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4161473-A 2,4,6-Trialkyl-3-hydroxyphenylalkane phosphonate and phosphinate stabilizers CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-3962376-A STABILIZERS, OXIDATION RESISTANCE, HEAT RESISTANCE, RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1976-06-08 US disclosed