Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124990 | 0.84 | PLA2G10 (0.47) | SLC7A5 | |
| SCHEMBL22689794 | 0.84 | SLC7A5 (0.65) | SLC7A5GRIA2ALPIPKMPTGS1 | |
| SCHEMBL22689792 | 0.84 | SLC7A5 (0.65) | SLC7A5GRIA2ALPIPKMPTGS1 | |
| SCHEMBL4329928 | 0.82 | LDHA (0.47) | LDHAMDM2CYP1A2SLC7A5TSHR | |
| SCHEMBL3471743 | 0.81 | HCAR2 (0.47) | LDHAMDM2 | |
| SCHEMBL4348571 | 0.79 | TDP1 (0.48) | LDHAMDM2CYP1A2SLC7A5FOLH1 | |
| SCHEMBL27785183 | 0.79 | HCAR2 (0.46) | LDHAMDM2 | |
| SCHEMBL491093 | 0.78 | GRIA2 (0.58) | LDHAMDM2CYP1A2GRIA2PKM | |
| SCHEMBL7440986 | 0.77 | CTBP2 (0.51) | LDHAMDM2ALDH1A1 | |
| SCHEMBL9456007 | 0.77 | GRIA2 (0.57) | MDM2CYP1A2CPA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175202-A | 4,5,6-Trinor-3,7,-inter-m-phenylene prostaglandin A1 analogs | THE UPJOHN COMPANY (US) | 1979-11-20 | — | — | US | disclosed |
| US-4084058-A | HYPOTENSIVES, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4053485-A | OPTICALLY ACTIVE OR RACEMIC MIXTURES | THE UPJOHN COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4032560-A | OXA PHENYLENE PROSTAGLANDIN ANALOGS | THE UPJOHN COMPANY (US) | 1977-06-28 | — | — | US | disclosed |
| US-4020097-A | HYPOTENSIVE, ANTICOAGULANT | THE UPJOHN COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
| US-3997566-A | Tricyclic prostaglandin | THE UPJOHN COMPANY (US) | 1976-12-14 | — | — | US | disclosed |