Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.47 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.47 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.47 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.47 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257100 | 0.91 | TBXAS1 (0.53) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL27731677 | 0.87 | PLA2G10 (0.45) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL1410876 | 0.84 | PLA2G10 (0.48) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL11529979 | 0.84 | LDHA (0.46) | SLC7A5 | |
| SCHEMBL14610928 | 0.83 | HPGD (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL10686705 | 0.83 | PTGES (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL31189307 | 0.83 | PTGES (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL20272563 | 0.83 | CYP1A2 (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL14870372 | 0.83 | PTGES (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL20272562 | 0.83 | PLA2G10 (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109809987-A | A kind of new synthetic method of loxoprofen sodium | 盘锦格林凯默科技有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-109809987-A | A kind of new synthetic method of loxoprofen sodium | 盘锦格林凯默科技有限公司 | 2019-05-28 | — | — | CN | disclosed |
| EP-2284157-A1 | Quinolines useful in treating cardiovascular disease | Wyeth (US) | 2011-02-16 | — | — | EP | disclosed |