Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.52 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.52 |
| ▸ | THRA | P10827 | 7/20 | 0.51 |
| ▸ | THRB | P10828 | 7/20 | 0.51 |
| ▸ | RARB | P10826 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414509 | 0.99 | PLK1 (0.54) | PLK1PLK3THRATHRBRARB | |
| SCHEMBL11526984 | 0.99 | PLK1 (0.54) | PLK1PLK3THRATHRBRARB | |
| SCHEMBL31483533 | 0.95 | PLK1 (0.54) | PLK1PLK3THRATHRBRARB | |
| SCHEMBL6936245 | 0.84 | THRA (0.56) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL2944041 | 0.84 | PLK1 (0.64) | PLK1PLK3RARBMEN1KMT2A | |
| SCHEMBL5422705 | 0.84 | PLK1 (0.56) | PLK1PLK3THRATHRBRARB | |
| SCHEMBL21362751 | 0.83 | ALDH1A1 (0.60) | PLK1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL918747 | 0.82 | PLK1 (0.66) | PLK1PLK3THRATHRBRARB | |
| SCHEMBL11530894 | 0.82 | PLK1 (0.52) | PLK1PLK3THRATHRBRARB | |
| SCHEMBL11527731 | 0.82 | PLK1 (0.55) | PLK1PLK3THRATHRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145444-A | 4-BUTYL-BENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4124726-A | 2-FLUORO-4'-ALKYLBENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |