Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526285 | 0.85 | ATM (0.35) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL11529927 | 0.81 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL11532124 | 0.78 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL9658898 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL11527442 | 0.74 | GAA (0.33) | ALDH1A1SMN1; SMN2TSHRKDM4EKMT2A | |
| SCHEMBL11092550 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL11092548 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL11528820 | 0.71 | RECQL (0.31) | — | |
| SCHEMBL11412055 | 0.71 | CYP3A4 (0.42) | ALDH1A1SMN1; SMN2KDM4EMAPTCYP2C9 | |
| SCHEMBL27912740 | 0.70 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |