Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532124 | 0.93 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL11533254 | 0.82 | L3MBTL1 (0.35) | MEN1KMT2AGAAPOLBRECQL | |
| SCHEMBL11530280 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL9658898 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL11412055 | 0.76 | CYP3A4 (0.42) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL8944648 | 0.70 | MEN1 (0.53) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL5087932 | 0.69 | GAA (0.37) | ALDH1A1KMT2AGAAPOLBSMN1; SMN2 | |
| SCHEMBL11846467 | 0.69 | GAA (0.43) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL15880150 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL8201307 | 0.68 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ANPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |