Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075790 | 0.84 | ALDH1A1 (0.74) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 | |
| Xenygloxal SCHEMBL2110325 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPK1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL11530261 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPK1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL13211669 | 0.82 | EGFR (0.54) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 | |
| SCHEMBL27580030 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 | |
| Xenygloxal SCHEMBL11410527 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1TDP1MAPTSMN1; SMN2 | |
| Xenygloxal SCHEMBL11411015 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL222221 | 0.81 | ALDH1A1 (0.74) | ALDH1A1MAPK1TDP1MAPTAKT1 | |
| Phenylglyoxal SCHEMBL5716642 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 | |
| Phenylglyoxal SCHEMBL57493 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147728-A | Disubstituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4064176-A | Di-substituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1977-12-20 | — | — | US | disclosed |