Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40016 | 0.73 | GAA (0.59) | GAAEZH2KMT2AMEN1MAPK1 | |
| SCHEMBL11528820 | 0.73 | RECQL (0.31) | — | |
| SCHEMBL11528566 | 0.71 | GAA (0.50) | GAAEZH2KMT2AMEN1MAPK1 | |
| SCHEMBL11530426 | 0.69 | EZH2 (0.47) | GAAEZH2KMT2AMEN1ALOX15 | |
| SCHEMBL79975 | 0.66 | KMT2A (0.52) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL6418982 | 0.66 | KMT2A (0.52) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL1898420 | 0.66 | KMT2A (0.52) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL1896538 | 0.65 | POLB (0.47) | KMT2AMEN1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL14760599 | 0.65 | POLB (0.47) | KMT2AMEN1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL11526285 | 0.64 | ATM (0.35) | GAAEZH2KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |