Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EZH2 | Q15910 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533254 | 0.75 | L3MBTL1 (0.35) | GAAEZH2KMT2AMEN1POLB | |
| SCHEMBL40016 | 0.74 | GAA (0.59) | GAAEZH2KMT2AMEN1MAPK1 | |
| SCHEMBL11530429 | 0.71 | GAA (0.43) | GAAEZH2KMT2AMEN1MAPK1 | |
| SCHEMBL28894376 | 0.71 | TSHR (0.60) | KMT2AMEN1MAPK1TSHRKDM4E | |
| SCHEMBL9639714 | 0.71 | TSHR (0.60) | KMT2AMEN1MAPK1TSHRKDM4E | |
| SCHEMBL11528562 | 0.70 | EZH2 (0.51) | GAAEZH2KMT2AMEN1POLB | |
| SCHEMBL3736621 | 0.70 | TSHR (0.50) | KMT2AMEN1MAPK1POLBTSHR | |
| SCHEMBL11526285 | 0.70 | ATM (0.35) | GAAEZH2KMT2AMEN1PKM | |
| SCHEMBL11532347 | 0.69 | EZH2 (0.56) | GAAEZH2KMT2AMEN1POLB | |
| SCHEMBL11445759 | 0.67 | GAA (0.51) | GAAEZH2KMT2APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |