Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11367723 | 0.93 | DAO (0.36) | DAOTSHRHIF1ALMNAHDAC3 | |
| SCHEMBL11321596 | 0.85 | BAZ2B (0.38) | DAOTSHRHRH2CYP3A4CYP2D6 | |
| SCHEMBL11374070 | 0.81 | CYP3A4 (0.37) | DAOTSHRHRH2CYP3A4CYP2D6 | |
| SCHEMBL8355751 | 0.79 | LMNA (0.55) | TSHRMAPTLMNAHRH3ALDH1A1 | |
| SCHEMBL11363580 | 0.79 | DAO (0.35) | DAOMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL11326227 | 0.77 | DAO (0.38) | DAOTSHRMAPTLMNAHDAC3 | |
| SCHEMBL11310363 | 0.77 | HRH2 (0.37) | DAOHRH2MAPTLMNAHRH4 | |
| SCHEMBL11364100 | 0.76 | HDAC3 (0.38) | TSHRLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL10857348 | 0.74 | DAO (0.40) | DAOTSHRCYP3A4CYP2D6HDAC3 | |
| SCHEMBL8352277 | 0.73 | TSHR (0.33) | TSHRHIF1AHRH2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137237-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |