Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111851 | 0.82 | MAPK1 (0.51) | LMNAALDH1A1CYP1A2TSHRMAPK1 | |
| Iodide SCHEMBL7279091 | 0.82 | ALDH1A1 (0.47) | LMNAALDH1A1CYP1A2TSHRMAPK1 | |
| SCHEMBL10310267 | 0.80 | HRH3 (0.56) | LMNAALDH1A1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL11530435 | 0.79 | DAO (0.36) | LMNAALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL8355552 | 0.79 | DAO (0.40) | LMNAALDH1A1SMN1; SMN2HPGDHTT | |
| Hydrochloric Acid SCHEMBL11198986 | 0.79 | LMNA (0.62) | LMNAALDH1A1CYP1A2TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL29074395 | 0.78 | LMNA (0.57) | LMNAALDH1A1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL11194269 | 0.78 | LMNA (0.50) | LMNAALDH1A1CYP1A2TSHRMAPK1 | |
| SCHEMBL10310339 | 0.78 | ALDH1A1 (0.61) | LMNAALDH1A1CYP1A2SMN1; SMN2HPGD | |
| SCHEMBL8351882 | 0.77 | ALDH1A1 (0.42) | LMNAALDH1A1TSHRSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952361-A | Compositions | DIAS NAHOUM CESAR ROBERTO (US) | 1999-09-14 | — | — | US | disclosed |
| US-5908853-A | THERAPY FOR SEXUAL DISORDERS | Nahoum, Cesar Roberto Dias (BR) | 1999-06-01 | — | — | US | disclosed |
| US-5773457-A | Compositions | Nahoum, Cesar Roberto Dias (BR) | 1998-06-30 | — | — | US | disclosed |