Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531727 | 0.89 | TSHR (0.40) | GAABCHETSHRCHRM2CHRM4 | |
| SCHEMBL11538938 | 0.86 | TSHR (0.40) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11534640 | 0.86 | GAA (0.41) | GAABCHETSHRCHRM2CHRM4 | |
| SCHEMBL11532899 | 0.86 | GAA (0.41) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11530973 | 0.85 | GAA (0.40) | GAABCHETSHRCHRM2CHRM4 | |
| SCHEMBL11533372 | 0.84 | SCN1A (0.43) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11532259 | 0.84 | GAA (0.39) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11539244 | 0.83 | BCHE (0.40) | GAABCHETSHRCHRM2CHRM4 | |
| SCHEMBL11533858 | 0.83 | KCNH2 (0.41) | GAATSHRKCNH2 | |
| SCHEMBL11534823 | 0.83 | GAA (0.44) | GAATSHRCHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |