Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130984 | 0.74 | GAA (0.41) | MAOBKDM4EATMNPSR1TDP1 | |
| SCHEMBL23833143 | 0.74 | NPSR1 (0.36) | MAOBKDM4EATMNPSR1TDP1 | |
| SCHEMBL4974601 | 0.73 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL11795941 | 0.73 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL22482041 | 0.72 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL23833112 | 0.72 | NPSR1 (0.47) | NPSR1TSHRALDH1A1 | |
| SCHEMBL11673147 | 0.71 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL172516 | 0.70 | MAPT (0.60) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8704294 | 0.70 | MAOA (0.43) | MAOBOPRM1TSHR | |
| SCHEMBL27220833 | 0.70 | CNR2 (0.40) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156730-A | CARBOXYALKYL-SUBSTITUTED PYRROLIDIN-3,5-DIONES | BEECHAM GROUP LIMITED (GB) | 1979-05-29 | — | — | US | disclosed |