Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525636 | 0.93 | KDM4E (0.39) | TXNRD1GSRMCHR1THRBTP53 | |
| SCHEMBL10637871 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10631445 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10637936 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10631831 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10637898 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10638065 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10631457 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10637864 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA | |
| SCHEMBL10634198 | 0.69 | THRB (0.53) | MCHR1THRBFAAHTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |