Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530685 | 0.93 | TXNRD1 (0.38) | TP53MAPTMCHR1THRBGSR | |
| SCHEMBL7027059 | 0.73 | — | — | |
| SCHEMBL10631511 | 0.66 | ALDH1A1 (0.46) | KDM4EHPGDPOLBTP53SMN1; SMN2 | |
| SCHEMBL3013104 | 0.64 | ALDH1A1 (0.80) | TP53SMN1; SMN2MAPTALDH1A1CYP3A4 | |
| SCHEMBL14426918 | 0.63 | NPC1 (0.50) | HPGDSMN1; SMN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10631412 | 0.63 | ALDH1A1 (0.44) | KDM4EHPGDPOLBTP53SMN1; SMN2 | |
| SCHEMBL7071890 | 0.62 | — | — | |
| SCHEMBL777886 | 0.62 | PSIP1 (0.64) | POLBTP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7971709 | 0.61 | THRB (0.37) | KDM4EHPGDPOLBALDH1A1CYP3A4 | |
| SCHEMBL10634274 | 0.61 | THRB (0.50) | ALDH1A1CYP3A4CYP2C9CYP2C19MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |