Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528610 | 0.99 | ALDH1A1 (0.39) | ALDH1A1TP53NPC1RAB9APAX8 | |
| SCHEMBL11537091 | 0.96 | ELANE (0.37) | ALDH1A1TP53NPC1RAB9APAX8 | |
| SCHEMBL11531654 | 0.90 | TP53 (0.38) | ALDH1A1TP53NPC1RAB9APAX8 | |
| SCHEMBL11529943 | 0.87 | ELANE (0.36) | ALDH1A1TP53ELANE | |
| SCHEMBL11528881 | 0.86 | KDM5A (0.36) | ALDH1A1TP53NPC1RAB9APAX8 | |
| SCHEMBL11533072 | 0.86 | ELANE (0.44) | ALDH1A1TP53NPC1RAB9APAX8 | |
| SCHEMBL11531229 | 0.86 | MLYCD (0.40) | TP53NPC1RAB9AELANE | |
| SCHEMBL11528434 | 0.86 | ELANE (0.36) | ALDH1A1TP53ELANE | |
| SCHEMBL11533009 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TP53NPC1RAB9APAX8 | |
| SCHEMBL11534704 | 0.83 | MLYCD (0.39) | ALDH1A1TP53NPC1RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |