Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.61 |
| ▸ | DAO | P14920 | 2/20 | 0.61 |
| ▸ | NSD2 | O96028 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988948 | 1.00 | CES1 (0.61) | CES1DAONSD2BCHETGM2 | |
| SCHEMBL25112387 | 0.79 | CES1 (0.77) | CES1DAONSD2BCHETGM2 | |
| SCHEMBL1247382 | 0.76 | CES1 (1.00) | CES1DAONSD2BCHETGM2 | |
| SCHEMBL29417367 | 0.76 | CES1 (1.00) | CES1DAONSD2BCHETGM2 | |
| SCHEMBL5987497 | 0.76 | GAA (0.47) | AGTR1POLBMAPTALDH1A1GAA | |
| SCHEMBL5740135 | 0.75 | CES1 (0.58) | CES1DAONSD2BCHETGM2 | |
| Methane SCHEMBL28522370 | 0.74 | CES1 (0.96) | CES1DAONSD2BCHETGM2 | |
| SCHEMBL9835981 | 0.72 | CES1 (0.61) | CES1TGM2GALR3IDO1 | |
| SCHEMBL5740595 | 0.72 | CES1 (0.61) | CES1TGM2GALR3IDO1 | |
| SCHEMBL3613979 | 0.71 | LRRK2 (0.62) | AGTR1GALR3POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160032-A | Oxindoles as sleep-inducers | SANDOZ, INC. (US) | 1979-07-03 | — | — | US | disclosed |