Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532343 | 0.99 | KCNA3 (0.43) | KCNA3RAB9ANPSR1CYP2D6MAPK1 | |
| SCHEMBL11535490 | 0.99 | KCNA3 (0.43) | KCNA3RAB9ANPSR1CYP2D6MAPK1 | |
| SCHEMBL11531523 | 0.87 | CYP3A4 (0.34) | CYP2D6SIGMAR1CYP3A4CHRM2CHRM1 | |
| SCHEMBL11533327 | 0.86 | KCNA3 (0.43) | KCNA3RAB9ANPSR1CYP2D6MAPK1 | |
| SCHEMBL11486790 | 0.85 | HRH3 (0.37) | RAB9ANPSR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11486857 | 0.84 | KCNA3 (0.41) | KCNA3CYP2D6MAPK1ALDH1A1KDM4E | |
| SCHEMBL11539299 | 0.84 | KCNA3 (0.53) | KCNA3RAB9ANPSR1CYP2D6MAPK1 | |
| SCHEMBL11474330 | 0.83 | HRH2 (0.34) | KCNA3MEN1KMT2AHRH3 | |
| SCHEMBL11533521 | 0.83 | KCNA3 (0.55) | KCNA3RAB9ANPSR1CYP2D6MAPK1 | |
| SCHEMBL11534012 | 0.83 | KCNA3 (0.55) | KCNA3RAB9ANPSR1CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153797-A | α-Aryl-α, α-bis[ω- (disubstituted amino)alkyl]acetamides and related compounds | G. D. SEARLE & CO. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4107205-A | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds | G. D. SEARLE & CO. (US) | 1978-08-15 | — | — | US | disclosed |