Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933915 | 0.93 | HTR2A (0.54) | HTR2AHTR2CIMPDH2IMPDH1AHR | |
| SCHEMBL28333783 | 0.73 | CHEK1 (0.49) | AHRSMN1; SMN2GAAALDH1A1EGFR | |
| SCHEMBL1921411 | 0.72 | AHR (0.50) | HTR2AHTR2CAHRSMN1; SMN2GAA | |
| SCHEMBL8912928 | 0.71 | HTR2A (0.65) | HTR2AHTR2CIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL3886120 | 0.71 | IMPDH2 (0.71) | HTR2AHTR2CIMPDH2IMPDH1SMN1; SMN2 | |
| Bromide SCHEMBL28157431 | 0.71 | AHR (0.48) | HTR2AHTR2CAHRSMN1; SMN2GAA | |
| Iodide SCHEMBL27978084 | 0.71 | AHR (0.48) | HTR2AHTR2CAHRSMN1; SMN2GAA | |
| SCHEMBL3188879 | 0.70 | AHR (0.44) | HTR2AHTR2CIMPDH2IMPDH1AHR | |
| SCHEMBL11375030 | 0.70 | IMPDH2 (0.44) | HTR2AHTR2CIMPDH2IMPDH1TRPA1 | |
| SCHEMBL933390 | 0.70 | HTR2A (0.51) | HTR2AHTR2CIMPDH2IMPDH1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144340-A | ADRENERGIC BLOCKING AGENTS | DEUTSCHE GOLD UND SILBER- SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-03-13 | — | — | US | disclosed |