Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920877 | 0.81 | HTT (0.50) | HTR2AHTR2CHTTALDH1A1TSHR | |
| SCHEMBL2009406 | 0.80 | KDM4E (0.60) | HTR2AHTR2CIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL31060568 | 0.79 | HTR2A (1.00) | HTR2AHTR2CHTTIMPDH2IMPDH1 | |
| SCHEMBL18509955 | 0.78 | HTR2A (0.63) | HTR2AHTR2CALDH1A1KDM4EPOLB | |
| SCHEMBL933915 | 0.77 | HTR2A (0.54) | HTR2AHTR2CIMPDH2IMPDH1TSHR | |
| SCHEMBL11248441 | 0.77 | HTR2A (0.55) | HTR2AHTR2CHTTIMPDH2IMPDH1 | |
| SCHEMBL18029085 | 0.75 | HTR2A (0.52) | HTR2AHTR2CALDH1A1TSHRKDM4E | |
| SCHEMBL14981556 | 0.72 | FBP1 (0.46) | HTR2AHTR2CHTTALDH1A1TSHR | |
| Chloroform SCHEMBL11530972 | 0.71 | HTR2A (0.49) | HTR2AHTR2CIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL7747845 | 0.71 | HTR2A (0.43) | HTR2AHTR2CIMPDH2IMPDH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | claimed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | claimed |