Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539766 | 0.89 | CYP11B1 (0.39) | KMT2AP2RX7TSHRCYP3A4CYP2C19 | |
| SCHEMBL11532238 | 0.84 | KIF11 (0.41) | CYP19A1KIF11CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL11537344 | 0.83 | CYP19A1 (0.40) | CYP19A1KMT2AMEN1CHRM2HTR1A | |
| SCHEMBL11533167 | 0.78 | CYP19A1 (0.38) | CYP19A1KMT2AMEN1CHRM2HTR1A | |
| SCHEMBL11531704 | 0.77 | KMT2A (0.38) | CYP19A1KMT2AMEN1KIF11BCL2 | |
| SCHEMBL11535559 | 0.76 | KIF11 (0.40) | CYP19A1KMT2AMEN1CHRM2HTR1A | |
| SCHEMBL11532022 | 0.76 | KMT2A (0.40) | CYP19A1KMT2AMEN1KIF11BCL2 | |
| SCHEMBL11533473 | 0.74 | CES1 (0.42) | KMT2AMEN1KIF11BCL2L3MBTL1 | |
| SCHEMBL11532067 | 0.74 | MEN1 (0.42) | CYP19A1KMT2AMEN1TSHR | |
| SCHEMBL9945358 | 0.73 | CYP19A1 (0.41) | CYP19A1KMT2AMEN1CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |