Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536693 | 0.91 | KCNN4 (0.34) | NPSR1KMT2AMEN1NR1I2CYP3A4 | |
| SCHEMBL11533167 | 0.88 | CYP19A1 (0.38) | KIF11BCL2NPSR1CHRM2HTR1A | |
| SCHEMBL11530796 | 0.77 | CYP19A1 (0.48) | KIF11BCL2NPSR1CYP19A1KMT2A | |
| SCHEMBL11535035 | 0.77 | KCNN4 (0.36) | CHRM2CHRM1CYP19A1MAPK1SMN1; SMN2 | |
| SCHEMBL11532016 | 0.76 | CYP19A1 (0.42) | KIF11BCL2CHRM2HTR1AADRA2A | |
| SCHEMBL11530455 | 0.73 | BCL2 (0.37) | KIF11BCL2NPSR1CYP19A1KMT2A | |
| SCHEMBL11537344 | 0.73 | CYP19A1 (0.40) | KIF11BCL2CHRM2HTR1AADRA2A | |
| SCHEMBL11532194 | 0.72 | BCL2 (0.39) | KIF11BCL2OPRM1DRD3KCNH2 | |
| SCHEMBL11532022 | 0.70 | KMT2A (0.40) | KIF11BCL2CYP19A1KMT2AL3MBTL1 | |
| SCHEMBL11533473 | 0.69 | CES1 (0.42) | KIF11BCL2KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |