Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532812 | 1.00 | LMNA (0.46) | LMNACA12CA1CA2CA7 | |
| SCHEMBL11534275 | 1.00 | LMNA (0.46) | LMNACA12CA1CA2CA7 | |
| SCHEMBL11535849 | 0.86 | LMNA (0.64) | LMNACXCR2TAS1R3TAS1R1 | |
| SCHEMBL11535136 | 0.86 | LMNA (0.43) | LMNACXCR2 | |
| SCHEMBL11535138 | 0.86 | LMNA (0.43) | LMNACXCR2 | |
| SCHEMBL11535534 | 0.86 | LMNA (0.43) | LMNACXCR2 | |
| SCHEMBL11269784 | 0.78 | LMNA (0.68) | LMNACA12CA1CA2CA7 | |
| SCHEMBL11493279 | 0.77 | LMNA (0.59) | LMNACXCR2 | |
| SCHEMBL11525540 | 0.77 | LMNA (0.59) | LMNACXCR2 | |
| SCHEMBL11527312 | 0.77 | LMNA (0.59) | LMNACXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150035-A | ANIMAL CROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| US-4150035-A | ANIMAL CROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-04-17 | — | — | US | disclosed |