SCHEMBL11269784

SCHEMBL11269784

CC(=O)NC1CCCc2sccc21

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.68
CXCR2 P25025 3/20 0.48
CYP11B1 P15538 5/20 0.42
CYP11B2 P19099 5/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
BRD3 Q15059 1/20 0.40
CCR6 P51684 1/20 0.39
HHAT Q5VTY9 1/20 0.39
PDE10A Q9Y233 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11535854 0.95 LMNA (0.74) LMNACXCR2CYP11B1CYP11B2CA12
SCHEMBL11267633 0.88 LMNA (0.69) LMNACXCR2CCR6PDE10A
SCHEMBL11483687 0.85 LMNA (0.92) LMNACXCR2CCR6
SCHEMBL11261936 0.84 LMNA (0.63) LMNACXCR2CCR6PDE10A
SCHEMBL11484087 0.84 LMNA (0.63) LMNACXCR2CA1CA2CCR6
SCHEMBL11490644 0.83 LMNA (0.70) LMNACXCR2CCR6
SCHEMBL11533685 0.82 LMNA (0.48) LMNACYP11B1CYP11B2CA12CA1
SCHEMBL11484122 0.82 LMNA (0.69) LMNACXCR2
SCHEMBL11492406 0.82 LMNA (0.61) LMNACXCR2CCR6PDE10A
SCHEMBL11492871 0.81 LMNA (0.67) LMNACXCR2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332724-A OXIDATION IN PRESENCE OF COBALT CATALYST AMERICAN CYANAMID CO. (US) 1982-06-01 US claimed
US-4254268-A OXIDIZED BY POTASSIUM PERMANGANATE AMERICAN CYANAMID COMPANY (US) 1981-03-03 US claimed
US-4332724-A OXIDATION IN PRESENCE OF COBALT CATALYST AMERICAN CYANAMID CO. (US) 1982-06-01 US disclosed
US-4254268-A OXIDIZED BY POTASSIUM PERMANGANATE AMERICAN CYANAMID COMPANY (US) 1981-03-03 US disclosed
US-4216149-A ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed
US-4199510-A Process for oxidation of 4-amidotetrahydrobenzo [b]-thiophenes to 7-keto derivatives with cobaltic salts AMERICAN CYANAMID COMPANY (US) 1980-04-22 US disclosed
US-4191830-A HERBICIDES AND ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1980-03-04 US disclosed
US-4156670-A UREAS AND THIOUREAS, HERBICIDES, ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1979-05-29 US disclosed
US-4134899-A Novel 4,5,6,7-tetrahydro-7-oxy(oxy)benzo [b]thiophen-4-amine compounds useful as animal growth regulants AMERICAN CYANAMID COMPANY (US) 1979-01-16 US disclosed
US-4069231-A ANIMAL GROWTH REGULATORS, HERBICIDES AMERICAN CYANAMID COMPANY (US) 1978-01-17 US disclosed
US-4053484-A 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo [b]thien-4-yl)ureas and 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo [b]thien-4-yl)ureas, novel intermediates for the preparation of animal growth promoting agents AMERICAN CYANAMID COMPANY (US) 1977-10-11 US disclosed
US-4036979-A ANIMAL GROWTH RATE ACCELERATOR AMERICAN CYANAMID COMPANY (US) 1977-07-19 US disclosed
US-3972895-A ANIMAL GROWTH REGULATOR, HERBICIDE AMERICAN CYANAMID COMPANY (US) 1976-08-03 US disclosed
US-3944567-A ANIMAL GROWTH REGULATOR, HERBICIDE AMERICAN CYANAMID COMPANY (US) 1976-03-16 US disclosed