SCHEMBL11533106

SCHEMBL11533106

CC(C)(Oc1ccc(/C=C/C(=O)c2ccccc2)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 5/20 0.69
▸ PPARA Q07869 5/20 0.69
▸ CYP3A4 P08684 3/20 0.67
▸ BCHE P06276 2/20 0.67
▸ NFKB1 P19838 2/20 0.67
▸ NFKB2 Q00653 2/20 0.67
▸ RELA Q04206 2/20 0.67
▸ MAPT P10636 4/20 0.62
▸ KMT2A Q03164 3/20 0.62
▸ RAB9A P51151 2/20 0.62
▸ NPC1 O15118 1/20 0.62
▸ ALDH1A1 P00352 2/20 0.59
▸ HPGD P15428 1/20 0.59
▸ MAOB P27338 4/20 0.58
▸ TNFRSF1A P19438 2/20 0.58
▸ CYP1B1 Q16678 2/20 0.58
▸ HSPD1 P10809 2/20 0.58
▸ HSPE1 P61604 2/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ PLIN1 O60240 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11533108 1.00 PPARG (0.69) PPARGPPARACYP3A4BCHENFKB1
SCHEMBL14491050 0.89 MAPT (0.66) PPARGPPARACYP3A4BCHENFKB1
SCHEMBL14491076 0.89 MAOB (0.66) PPARGPPARACYP3A4BCHENFKB1
SCHEMBL814358 0.89 MAPT (0.66) PPARGPPARACYP3A4BCHENFKB1
SCHEMBL14523081 0.89 MAOB (0.66) PPARGPPARACYP3A4BCHENFKB1
SCHEMBL25205883 0.89 MAPT (0.66) PPARGPPARACYP3A4BCHENFKB1
SCHEMBL11536172 0.88 CYP3A4 (0.66) PPARGPPARACYP3A4BCHENFKB1
SCHEMBL814724 0.88 MAOB (0.67) PPARGPPARACYP3A4MAPTKMT2A
SCHEMBL11782573 0.88 MAOB (0.67) PPARGPPARACYP3A4MAPTKMT2A
SCHEMBL25192163 0.88 MAOB (0.67) PPARGPPARACYP3A4MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
US-4163859-A ANTILIPEMIC, FUNGICIDES, BACTERICIDES G. D. SEARLE & CO. (US) 1979-08-07 — — US disclosed
US-3994955-A Substituted phenoxydialkylacetic acids and esters G. D. SEARLE & CO. (US) 1976-11-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B PPARG 4105/4885PPARA 4345/4885CYP3A4 928/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 PPARG 3395/4885PPARA 4095/4885CYP3A4 1589/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 PPARG 3395/4885PPARA 4095/4885CYP3A4 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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