SCHEMBL25192163

SCHEMBL25192163

CC(C)(Oc1ccc(C(=O)C=Cc2ccc(Cl)cc2)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 7/20 0.67
▸ MAOA P21397 2/20 0.67
▸ PPARA Q07869 4/20 0.66
▸ PPARG P37231 3/20 0.66
▸ FABP2 P12104 1/20 0.66
▸ SLC22A12 Q96S37 1/20 0.66
▸ MAPT P10636 2/20 0.66
▸ MEN1 O00255 1/20 0.66
▸ CYP1A2 P05177 1/20 0.66
▸ CYP3A4 P08684 1/20 0.66
▸ CYP2D6 P10635 1/20 0.66
▸ CYP2C19 P33261 1/20 0.66
▸ KMT2A Q03164 1/20 0.66
▸ CYP1B1 Q16678 1/20 0.58
▸ CXCL12 P48061 1/20 0.57
▸ F3 P13726 1/20 0.55
▸ ABCG2 Q9UNQ0 2/20 0.54
▸ XDH P47989 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11782573 1.00 MAOB (0.67) MAOBMAOAPPARAPPARGFABP2
SCHEMBL814724 1.00 MAOB (0.67) MAOBMAOAPPARAPPARGFABP2
SCHEMBL14491076 0.88 MAOB (0.66) MAOBMAOAPPARAPPARGMAPT
SCHEMBL14523081 0.88 MAOB (0.66) MAOBMAOAPPARAPPARGMAPT
SCHEMBL25205883 0.88 MAPT (0.66) MAOBMAOAPPARAPPARGMAPT
SCHEMBL814358 0.88 MAPT (0.66) MAOBMAOAPPARAPPARGMAPT
SCHEMBL14491050 0.88 MAPT (0.66) MAOBMAOAPPARAPPARGMAPT
SCHEMBL11533106 0.88 PPARG (0.69) MAOBMAOAPPARAPPARGMAPT
SCHEMBL11533108 0.88 PPARG (0.69) MAOBMAOAPPARAPPARGMAPT
SCHEMBL25193908 0.85 PPARG (0.69) PPARAPPARGMAPTMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885MAOA 1902/4885PPARA 4345/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAOA 3145/4885PPARA 4095/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAOA 3145/4885PPARA 4095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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