Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533119 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAPKMHTTHSD17B10 | |
| SCHEMBL11853020 | 0.87 | FFAR1 (0.42) | ALDH1A1LMNAHTTHSD17B10SMN1; SMN2 | |
| SCHEMBL11530902 | 0.81 | TSHR (0.39) | ALDH1A1HTTHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL11530907 | 0.81 | TSHR (0.39) | ALDH1A1HTTHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL11532667 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1LMNAPKMHSD17B10SMN1; SMN2 | |
| SCHEMBL11532668 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1LMNAPKMHSD17B10SMN1; SMN2 | |
| SCHEMBL11680453 | 0.78 | RAB9A (0.37) | ALDH1A1LMNAHTTHSD17B10SMN1; SMN2 | |
| SCHEMBL11532626 | 0.77 | KMT2A (0.54) | ALDH1A1PKMHTTSMN1; SMN2KDM4E | |
| SCHEMBL11532623 | 0.77 | KMT2A (0.54) | ALDH1A1PKMHTTSMN1; SMN2KDM4E | |
| SCHEMBL11533151 | 0.76 | RAB9A (0.45) | ALDH1A1LMNAPKMHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118389-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1978-10-03 | — | — | US | claimed |
| US-4156082-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4154733-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154732-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4118389-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |