SCHEMBL11533142

SCHEMBL11533142

CCCCCCCCCCN1C(=O)C2C3C=CC(C3)C2C1=O

nearest known ligand 0.83

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.83
KMT2A Q03164 2/20 0.83
RAB9A P51151 2/20 0.83
ALDH1A1 P00352 5/20 0.80
HTT P42858 2/20 0.66
TSHR P16473 2/20 0.66
USP2 O75604 1/20 0.66
HSD17B10 Q99714 1/20 0.66
KDM4E B2RXH2 1/20 0.59
CNR2 P34972 3/20 0.56
CNR1 P21554 1/20 0.56
MAPK1 P28482 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.53
LMNA P02545 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
MGLL Q99685 2/20 0.49
PTGS1 P23219 2/20 0.49
PTGS2 P35354 2/20 0.49
FAAH O00519 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10625208 1.00 MEN1 (0.83) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL11528094 1.00 MEN1 (0.83) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL16231138 1.00 MEN1 (0.83) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL17300529 1.00 MEN1 (0.83) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL11592112 1.00 MEN1 (0.83) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL11594277 0.98 ALDH1A1 (0.83) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL11529889 0.93 ALDH1A1 (0.79) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL13864157 0.91 MEN1 (0.69) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL13864170 0.91 MEN1 (1.00) MEN1KMT2ARAB9AALDH1A1HTT
SCHEMBL13864169 0.91 MEN1 (0.69) MEN1KMT2ARAB9AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132750-A RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES SHOWA DENKO K.K. (JP) 1979-01-02 US disclosed
US-4105608-A HIGH IMPACT COMPOSITION OF RING-OPENING POLYMERIZATION PRODUCT SHOWA DENKO K.K. (JP) 1978-08-08 US disclosed
US-4059561-A AND A HALOGEN COMPOUND SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed
US-4028482-A LOW VISCOSITY POLYALKENAMER SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-06-07 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3959234-A CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-05-25 US disclosed