Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504746 | 0.84 | MAPT (0.43) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL11526292 | 0.81 | TDP1 (0.56) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL3306947 | 0.78 | ALDH1A1 (0.47) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL3977319 | 0.77 | MAPK1 (0.40) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL11533450 | 0.77 | MAPK1 (0.40) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL11533356 | 0.75 | MAPK1 (0.41) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL11535247 | 0.75 | MAPK1 (0.41) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL11526277 | 0.75 | MAPK1 (0.41) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL11528700 | 0.74 | TDP1 (0.37) | TDP1MAPK1CYP3A4TSHRTRPA1 | |
| SCHEMBL11517806 | 0.73 | MAPK1 (0.52) | TDP1MAPK1CYP3A4TSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |