Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531173 | 0.93 | TSHR (0.46) | TSHRCYP3A4CYP19A1RAB9APOLB | |
| SCHEMBL11539190 | 0.93 | TSHR (0.54) | TSHRCYP3A4CYP19A1RAB9AATM | |
| SCHEMBL11536569 | 0.90 | TSHR (0.51) | TSHRCYP3A4CYP19A1RAB9AATM | |
| SCHEMBL11535471 | 0.88 | TSHR (0.58) | TSHRCYP3A4CYP19A1RAB9AATM | |
| SCHEMBL11534709 | 0.88 | TSHR (0.47) | TSHRCYP3A4CYP19A1RAB9APOLB | |
| SCHEMBL11533550 | 0.88 | TSHR (0.44) | TSHRCYP19A1RAB9ALMNAKMT2A | |
| SCHEMBL11534596 | 0.87 | CYP19A1 (0.55) | TSHRCYP19A1RAB9ALMNAKMT2A | |
| SCHEMBL11537539 | 0.87 | TSHR (0.46) | TSHRCYP3A4CYP19A1RAB9ALMNA | |
| SCHEMBL11538888 | 0.86 | MAPT (0.47) | TSHRCYP3A4CYP19A1RAB9ALMNA | |
| SCHEMBL11532830 | 0.86 | LMNA (0.50) | TSHRCYP3A4CYP19A1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |