Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537539 | 0.97 | TSHR (0.46) | TSHRSMN1; SMN2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL11534743 | 0.93 | CYP19A1 (0.44) | TSHRSMN1; SMN2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL11531901 | 0.93 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL11531685 | 0.92 | SMN1; SMN2 (0.47) | TSHRSMN1; SMN2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL11532826 | 0.91 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2CYP3A4ALDH1A1HTT | |
| SCHEMBL11533723 | 0.90 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2CYP3A4ALDH1A1MEN1 | |
| SCHEMBL11531469 | 0.89 | SMN1; SMN2 (0.47) | TSHRSMN1; SMN2CYP3A4ALDH1A1HTT | |
| SCHEMBL11533266 | 0.88 | TSHR (0.56) | TSHRSMN1; SMN2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL11570831 | 0.87 | CYP19A1 (0.42) | TSHRSMN1; SMN2CYP19A1ALDH1A1MEN1 | |
| SCHEMBL11539604 | 0.86 | CYP19A1 (0.53) | TSHRCYP19A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |