Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966807 | 0.82 | MAPT (1.00) | MAPTHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL12647098 | 0.82 | MAPT (1.00) | MAPTHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL1053506 | 0.82 | MAPT (0.93) | MAPTHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL1613666 | 0.81 | MAPT (0.90) | MAPTHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL11533902 | 0.80 | LMNA (0.55) | MAPTHSD17B10ALDH1A1LMNABAZ2B | |
| SCHEMBL11530996 | 0.80 | KDM4E (0.54) | HSD17B10ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30982079 | 0.74 | HSD17B10 (1.00) | MAPTHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL12868471 | 0.71 | MAPT (0.62) | MAPTHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL1004931 | 0.69 | MAPT (0.70) | MAPTHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL6627508 | 0.69 | MAPT (0.75) | MAPTHSD17B10ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144349-A | N,N-dimethyl-1,2,4,5,6,7-hexahydrothiocino[5,4-b]-indole-7-propanamine-3,3-dioxides and related thiocines | WARNER-LAMBERT COMPANY (US) | 1979-03-13 | — | — | US | claimed |
| US-4144349-A | N,N-dimethyl-1,2,4,5,6,7-hexahydrothiocino[5,4-b]-indole-7-propanamine-3,3-dioxides and related thiocines | WARNER-LAMBERT COMPANY (US) | 1979-03-13 | — | — | US | disclosed |